Prostaglandin E ₂ Production After Lamellar Keratectomy and Photorefractive Keratectomy

Abstract

Mechanical and photochemical superficial keratectomies induce production of an inflammatory mediator, PGE2. The 193-nanometer excimer laser irradiation causes a greater increase of PGE2 production in the corneal tissue than does keratectomy with the microkeratome; this observation may support a role for cyclo-oxygenase inhibitors in postoperative therapy.