Generalized tuberous xanthoma with type IV hyperlipoproteinemia.

Abstract

We report a case of generalized tuberous xanthoma with type IV hyperlipoproteinemia in a 42-year-old woman who had multiple, grouped, yellowish brown nodules bilaterally on the trunk, knees, elbows, palms, soles, and dorsal sides of multiple interphalangeal joints. On laboratory examination, serum triglyceride levels were elevated, and the pre-beta-lipoprotein band was increased on lipoprotein electrophoresis. Histopathologic findings showed many Touton giant cells and numerous foam cells in the dermis.