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Correction of thrombocytopenia with dapsone in the primary antiphospholipid syndrome.
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1993
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ThrombopoiesisThrombosisVenous ThrombosisBlood PlateletSevere ThrombocytopeniaHematologyPharmacologyPathologyPrimary Antiphospholipid SyndromeAntiphospholipid SyndromePlatelet AntagonistMedicineAtherosclerosisApparent Therapeutic Effect
A 25-year-old woman with the antiphospholipid syndrome developed severe thrombocytopenia (18 x 10(9)/l), which was promptly corrected by treatment with dapsone. The mechanisms for the apparent therapeutic effect of dapsone are discussed.