PubMed · 1975 · 44 citations · 0 references
PharmacyGeneticsToxicologyCytogeneticsHeavy Metal ToxicologyOccupational ToxicologyCadmium ToxicologyEnvironmental Heavy Metal ExposureHeavy Metal ContaminationMetal ToxicityOccupational Heavy Metal ExposureZinc ToxicityCadmium ContaminationChromosome Structural AberrationsCytogenetic AbnormalitiesDicentric ChromosomesEnvironmental Cadmium ExposureHeavy Metal GenotoxicityStructural Chromosomal AberrationsStructural Chromosome Aberrations
Chromosome analysis has been performed on workers from a cadmium plant who were exposed to fumes and dust of cadmium and lead. The 35 workers were classified, according to the type and duration of exposure, into a group (cadmium service) exposed to high levels of lead and cadmium in the absence of zinc (23 people) and a group of rolling-mill workers subjected mostly to zinc but also to lower levels of lead and cadmium (12 people). A higher yield of severe chromosome anomalies (chromatid exchange, disturbance of spiralization, chromosome translocation, ring and dicentric chromosomes) together with a total lower number of structural aberrations was observed in the cadmium workers when compared with the rolling-mill group.