Cytomegalovirus retinitis: two cases occurring after renal transplantation.

Abstract

Cytomegalovirus (CMV) retinitis is reported in 2 patients who received immunosuppressive medication after cadaveric renal transplantation. The clinical features of this disease as well as the differential diagnosis are presented. Reduction in the amount of immunosuppressive drugs given postoperatively is suggested as the definitive treatment of this disease. Available specific antiviral chemotherapeutic agents were ineffective against CMV retinitis. This finding may be modified at a later date, with the introduction and use of new effective and safe antiviral drugs.