Relationship of maximal tubular phosphate reabsorption to filtration rate in the dog

Abstract

A maximal renal tubular rate of reabsorption of phosphate (Tm p ) has been demonstrated in the normal dog. In the dog, as in the man, considerable variability in the Tm p often occurs. While some of this variability remains unexplained, a direct relationship between glomerular filtration rate (GFR) and Tm p can be demonstrated when the GFR is varied over a wide range. This relationship suggests that glomerular intermittency may exist in the dog.