Concepedia

Metastasectomy and active specific immunotherapy for a large single melanoma metastasis.

Arnold Baars, J.M.G.H. van Riel, M. A. Cuesta, Elisabeth H. Jaspars, Herbert M. Pinedo, Alfons J.M. van den Eertwegh

PubMed · 2002 · 16 citations · 0 references

Concepts

MedicineOncologySurgeryImmunotherapyMetastasisSurgical OncologyAdjuvant ImmunotherapyCancer ImmunotherapyCombination ImmunotherapyImmunotherapy For Skin CancerMelanoma SurgeryMetastatic Disease SurgeryAutologous Immune Cell TherapyAutologous Tumor Cell VaccinesDuodenal CancerMelanoma ImmunotherapyMetastatic Melanoma TreatmentRecurrence-free SurvivalSurgical Metastasectomy

Abstract

A patient with a large duodenal melanoma metastasis, involving adjacent jejunum and colon, is presented. Treatment consisted of a combination of radical surgery and active specific immunotherapy by means of an autologous tumor cell vaccine and BCG after which a recurrence-free survival of now more than 10 years has been observed. The role of surgery and immunotherapy in the treatment of metastatic melanoma are discussed.