Concepedia

Publication | Closed Access

Tumor-induced dysfunction in interleukin-2 production and interleukin-2 receptor signaling: a mechanism of immune escape.

37

Citations

0

References

2000

Year

Patricia Rayman, Robert G. Uzzo, Vladimir Kolenko, Tracy Bloom, Martha K. Cathcart, Luis Moltó, A C Novick, Ronald M. Bukowski, Thomas A. Hamilton, James H. Finke
PubMed

Abstract

These findings suggest that soluble products from renal tumors may suppress T-cell responses by blocking both IL-2 production and normal IL-2 receptor signaling.