Concepedia

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Prognostic significance of Ape1/ref-1 subcellular localization in non-small cell lung carcinomas.

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Citations

0

References

2002

Year

Fabio Puglisi, G. Aprile, Alessandro Marco Minisini, Fabio Barbone, Palmina Cataldi, Gianluca Tell, Mark R. Kelley, Giuseppe Damante, Carlo Alberto Beltrami, Carla Di Loreto
PubMed

Abstract

The results suggest a potential role of Ape1/ref-1 sub-cellular localization as a prognostic indicator in patients with NSCLC. In particular, cytoplasmic localization of the protein seems to confer a poor outcome in subgroups of patients with nodal involvement or adenocarcinoma histotype.