Growth and Transovarial Transmission of Chandipura Virus (Rhabdoviridae: Vesiculovirus) in Phlebotomus Papatasi

Abstract

Chandipura virus multipled in sand flies (Phlebotomus papatasi) following intrathoracic inoculation. Within 24 hours, mean virus titers in infected flies increased approximately 4 logs. Experimentally infected P. papatasi transmitted the virus by bite to newborn mice and by transovarial transmission to their progeny. Eight percent of the F1 offspring of experimentally infected female parents were infected with Chandipura virus.