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Somatosensory evoked potentials in Huntington's disease--studies with paired stimulation.
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1989
Year
Second Sep AmplitudesNeurobiology Of DiseaseNeurophysiologyNeuroanatomySep AmplitudeMedicineNeurological FunctionPaired StimulationRehabilitationNeuroscienceNeurologyBrain ElectrophysiologyCentral Nervous SystemNeurorehabilitationNervous SystemBrain StimulationNeurostimulationSocial Sciences
The somatosensory evoked potentials (SEPs) and recovery functions of the SEP with paired stimulation were studied in patients with Huntington's disease (HD). A significant decrease in amplitude of the SEP was observed in 4 of the 5 patients. In addition, with paired stimulation, the second SEP amplitudes were normalized at intervals of about 10 ms. These findings possibly suggest that functional block rather than organic change in the thalamus may play an important role in the reduction in SEP amplitude in HD.