Reduction of Th1 cell activity in the peripheral circulation of patients with rheumatoid arthritis after treatment with a non-depleting humanized monoclonal antibody to CD4. - Concepedia

Concepedia

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Reduction of Th1 cell activity in the peripheral circulation of patients with rheumatoid arthritis after treatment with a non-depleting humanized monoclonal antibody to CD4.

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References

1998

Year

Hendrik Schulze‐Koops, Laurie S. Davis, Thomas P. Haverty, Mary C. Wacholtz, Peter E. Lipsky

Abstract

Clinical improvement in patients with RA treated with a non-depleting Mab to CD4 may be related to a decrease in the function of IL-2 and IFN-gamma producing Th1 cells.