Inhibitory effects of mesial temporal partial seizures onto frontal neocortical structures.

Abstract

Secondary involvement of neocortical temporal structures in ictal rCBF-SPECT with 99mTc-ECD occurs early and focal maxima of tracer uptake within the temporal lobe do not necessarily represent the epileptogenic focus itself. Seizures of mesial temporal origin did not activate but frequently depressed the ipsilateral basal frontal tracer uptake during the early ictal phase. This phenomenon may account for some aspects of the clinical appearance of mesial temporal seizures.