Chronic isolation of adult rats decreases gene expression of catecholamine biosynthetic enzymes in adrenal medulla.

Abstract

We can conclude that psychosocial stress expressed a differential influence on gene expression and protein levels of catecholamine biosynthetic enzymes in the adrenal medulla of adult rats. The results indicate a possible adaptation of catecholamine-synthesizing system at the level of TH gene expression in adrenal medulla of chronically isolated animals.