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Interleukin 18 levels reflect the severity of acute pancreatitis.
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2001
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InflammationAutoimmune DiseaseHepatologyImmunologyInflammation BiologyChronic InflammationPathologyAutoimmunityLiver DysfunctionInflammatory MarkerImmune SystemMedicineInflammatory DiseaseIl-18 LevelsAutoimmune Liver DiseaseAcute Pancreatitis
The serum interleukin 18 (IL-18) levels were significantly increased in cases of acute pancreatitis, corresponding to the severity of the disease. The IL-18 levels were also significantly correlated with the serum tumor necrosis factor alpha (TNF-alpha) and bilirubin levels. The possible involvement of IL-18 in the development of liver dysfunction in acute pancreatitis is suggested.