Perspectives on the Positive and Negative Syndrome Scale (Panss): Use, Misuse, Drawbacks, and A New Alternative for Schizophrenia Research

Abstract

The PANSS is a reliable and valid instrument that has served the scientific research community well for decades. New advances in experimental psychopathology and personalized psychiatry and the new National Institute of Mental Health paradigm of Research Domain Criteria necessitate a new instrument compatible with advances in clinical neuroscience research.