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[Vascular endothelial growth factor (VEGF) and its role in neoplastic processes].
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2001
Year
Functional PropertiesPathologyTumor BiologyAngiogenesisCancer Cell BiologyAlternative SplicingRadiation OncologyCancer ResearchHealth SciencesEndothelial Cell PathobiologyVascular BiologyNeovascularizationVascular Endothelial Growth FactorCell BiologyTumor MicroenvironmentNeoplastic ProcessesEndothelial DysfunctionMedicineCancer GrowthVegf Gene Transcription
This review concerns structural and functional properties of human vascular endothelial growth factor as well as the process of alternative splicing of its transcript. Regulation of VEGF gene transcription and participation of the protein in the angiogenesis of tumours are also broadly discussed.