RHEUMATOID ARTHRITIS TREATED WITH CHLORAMBUCIL: A FIVE‐YEAR FOLLOW‐UP

Abstract

The results of a five-year study of chlorambucil in patients suffering from rheumatoid arthritis are presented. The effect of treatment was to allow a reduction in corticosteroid dosage and a sustained remission of disease activity in patients. Three patients of the series of 22 developed neoplastic disease, and the signficance of this is discussed.