Prolactin hormone in juvenile systemic lupus erythematosus: a possible relationship to disease activity and CNS manifestations.

Abstract

Our results suggest a subset of juvenile SLE characterized by hyperprolactinemia and increased prevalence of CNS manifestations. A possible relationship between serum PRL concentrations and disease activity in juvenile SLE was found. Our data point to the importance of further studies of the role of PRL in immunomodulation of pediatric rheumatic diseases.