Palladium(II)-Catalyzed Direct C–H Alkenylation of Thienothiophene and Related Fused Heteroarenes

Abstract

The palladium-catalyzed direct alkenylation of thieno[3,2-b]thiophene takes place regioselectively at C2. Symmetrically and unsymmetrically 2,5-dialkenylated thienothiophene derivatives can be prepared by the catalytic procedure. Related fused thienyl and carbazole derivatives also undergo regioselective direct alkenylation.