Publication | Closed Access
[Model building in pharmacokinetics/Part III: Simplified rules for the deduction of analytical solutions for linear compartment models (author's transl)].
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Citations
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References
1977
Year
Applied Mathematical ModellingSimple RulesEngineeringModeling MethodComputational MechanicsPhysiologically-based Pharmacokinetic ModelingPharmacokinetics/part IiiMolecular PharmacologySystems EngineeringLinear Compartment ModelModeling And SimulationSystems AnalysisDrug AnalysisPharmacokinetic ModelingPopulation Balance ModelingLinear Compartment ModelsDifferential EquationsPharmacologyAnalytical SolutionsPhysiologyMedicinePharmacokineticsMultiscale Modeling
Analytical solutions for any linear compartment model are obtained empirically by use of simple rules. Set up of differential equations and tedious integration procedures are thus avoided. The procedure is suited for automation by a calculator. Integrated equations are accessible then even more simply and rapidly.