Hydrogen peroxide preconditioning enhances the therapeutic efficacy of Wharton's Jelly mesenchymal stem cells after myocardial infarction. - Concepedia

Concepedia

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Hydrogen peroxide preconditioning enhances the therapeutic efficacy of Wharton's Jelly mesenchymal stem cells after myocardial infarction.

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References

2012

Year

Jin Zhang, Guanghui Chen, Yongwei Wang, Jing Zhao, Haifeng Duan, Lianming Liao, Xiaozhong Zhang, Yundai Chen, Chen Hu

Abstract

This study demonstrates that H2O2 preconditioning significantly enhanced the therapeutic potential of WJ-MSCs, possibly by stimulating the production of IL-6 by WJ-MSCs, which may cause migration and proliferation of endothelial cells and increase neovascularization.