Importance of glycation in the acceleration of low density lipoprotein (LDL) uptake into macrophages in patients with diabetes mellitus.

Abstract

The results indicate that the greater uptake of DM-LDL than that of control LDL may be attributed to glycation of LDL caused by hyperglycemia in diabetic patients. Glycation of LDL by hyperglycemia may be one cause of the accelerated atherogenesis in diabetic patients.