Adequacy of Perfusion during Hypothermia: Regional Distribution of Cardiopulmonary Bypass Flow, Mixed Venous and Regional Venous Oxygen Saturation

Abstract

During hypothermic CPB, regional deoxygenation occurs in spite of normal mixed venous saturation. The level of hypothermia has a major impact on bypass flow distribution with cerebral perfusion reduction. Methods of regional oxygenation assessment are needed, and altered strategies during hypothermia have to be taken into consideration.