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Anthracycline-induced cardiotoxicity: risk assessment and management.
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2009
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Dose IntensityPharmacotherapyCardiovascular ToxicityRadiation MedicineToxicologyClinical Radiation OncologyRadiation OncologyCardiologyCancer ResearchMyocardial InfarctionHealth SciencesRadiation TherapyMedicineRiskCancer TreatmentAnthracycline-induced CardiotoxicityRisk FactorsCumulative DoseCardiovascular DiseaseOncology
In the current issue of ONCOLOGY, Hershman and Shao provide a comprehensive review of anthracycline-induced cardiotoxicity (AIC). Risk factors for AIC include age (≤ 18 or ≥ 65 years) at time of treatment, increasing cumulative dose or dose intensity of anthracyclines, mediastinal radiation therapy (RT), and female gender.[1-4]