PubMed · 1989 · 21 citations · 0 references
PharmacyEnvironmental SciencesToxicologyEnvironmental ToxicologyIndustrial ToxicologyToxicodynamicsAcute ToxicityChemical Hazard AssessmentChemical SafetyExposure AssessmentHousehold Chemical ToxicityAcute Tissue ToxicityAdditivesChemical Food AdditivesChemical-induced Acute ToxicityOrgan Toxicity Evaluation
Acute toxicity tests on 113 environmental chemicals were conducted by the order of the Japanese government agencies. the LD50s or LC50s for 23 household chemicals, 11 medical drugs, 10 drug additives, 20 food additives, 13 industrial chemicals, 14 environmental pollutants, 12 agricultural chemicals and 5 organic solvents are presented together with the major toxic signs and symptoms and macroscopic changes in tissues. These toxicity data will be useful as an information source for regulatory purposes and also for prediction of the potential for acute toxicity of a wide variety of new chemicals.