Characterization of canine MDR1 mRNA: its abundance in drug resistant cell lines and in vivo. - Concepedia

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Characterization of canine MDR1 mRNA: its abundance in drug resistant cell lines and in vivo.

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References

1998

Year

Samantha Steingold, N J Sharp, M. Christine McGahan, Christine S. Hughes, Sandra E. Dunn, R L Page

Abstract

We conclude that the canine MDR1 mRNA homologue is structurally similar to the human transcript. Expression of MDR1 mRNA correlates with in vitro drug sensitivity but does not correlate with in vivo doxorubicin sensitivity in canine lymphoma.