Acta Dermato Venereologica · 1990 · 13 citations · 0 references
MedicinePharmacologyPharmacotherapyEndocrine PharmacotherapyNeuropharmacologyPsychopharmacologyAppetiteAppetite AssessmentAppetite RegulationCachexia ManagementWeight LossWithdrawal SyndromesAnorexia-cachexia SyndromeAppetite Regulation During IllnessAppetite SuppressantsDepression SymptomatologyHormonal AlterationsHormonal Regulation Of AppetiteMedication Effects On AppetiteMedication-induced Appetite Changes
A man with AIDS is described in whom a profound weight loss was converted into a weight gain by treatment with megoestrol acetate, a synthetic progesterone. His appetite improved and was accompanied by a feeling of improved well-being. Following abrupt discontinuation of the drug, there was a significant but transient depression of mood and appetite associated with loss of energy; it is suggested that this complex of symptoms might represent a megoestrol acetate withdrawal-associated syndrome.