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Y-chromosome-specific haplotype diversity in Ashkenazic and Sephardic Jews.
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1993
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Genetic AnalysisHaplotype DeterminationGenetic TestingEuropean HaplotypesMolecular EcologyCytogeneticsGeneticsHaplotype DistributionsY-chromosome-specific Haplotype DiversityHuman PolymorphismStatistical GeneticsGenetic VariationGenomicsPublic HealthMedicineDna Samples
DNA samples from Ashkenazic and Sephardic Jews were studied with Y-chromosome-specific DNA probes p49f and p49a to screen for RFLPs and haplotypes. All 16 European haplotypes were found in Jews, but only 2 of them (VII and VIII) were widespread. Haplotype distributions in the two Jewish populations are similar, but haplotypes XI and XV are more frequent in the Ashkenazim and haplotypes IV and V are more frequent in the Sephardim, indicating their origins.