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Metalloporphyrin contrast agents for magnetic resonance imaging of human tumors in mice.
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1986
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EngineeringOncologic ImagingImaging AgentEnhanced ContrastPathologyTumor BiologyMagnetic Resonance ImagingMagnetic Resonance ImagesRadiopharmaceutical TherapyRadiation OncologyWater-soluble PorphyrinsNuclear MedicineMolecular ImagingCancer ResearchRadiologyHuman TumorsMedicineContrast AgentPharmacologyTumor MicroenvironmentMetalloporphyrin Contrast AgentsBiomedical ImagingOncology
Enhanced contrast of transplanted human colon carcinoma in athymic mice is seen in magnetic resonance images upon iv injection of the complexes of Mn(III) with two water-soluble porphyrins, tetra (4-sulfonatophenyl) porphyrin and tetra (N-methyl-4-pyridyl) porphyrin.