Journal of the American Veterinary Medical Association · 1988 · 45 citations · 0 references
MedicineVeterinary Diagnostic ImagingVeterinary PathologyEndocrine OncologyNecropsy PathologyTumor PathologyAdrenal DisordersAdrenal EndocrinologyAdrenal Mass EvaluationAdrenal TumorsPituitary DisordersPituitary TumorsAdrenal Adenoma ImagingAdrenal AdenomasAdrenal NeoplasiaAdrenal Tumor DiagnosisAdrenocorticotropic Hormone-secreting Pituitary TumorsHistologic ExaminationPituitary Tumor HistopathologyPituitary Tumor Pathology
Computed tomography (CT) was performed in 10 dogs with hyperadrenocorticism not suppressible by dexamethasone. In 6 of these dogs, a unilateral adrenal mass was found on CT images. Specimens of the masses were obtained via retroperitoneal laparotomy; histologic examination revealed 4 carcinomas, 1 adenoma, and 1 nodular hyperplasia. In the 4 other dogs, CT revealed symmetric bilateral adrenal gland enlargement. In 2 of these dogs, contrast-enhanced CT revealed a mass in the pituitary fossa, which could be identified at necropsy as a pituitary tumor. The other 2 dogs were successfully treated with mitotane.