Radiation Protection Dosimetry · 1994 · 35 citations · 0 references
PharmacyToxicologyExcretionRadiation DosimetryRadiobiologyExcretion KineticsExcretion ModelingRenal ExcretionUrinary ExcretionCumulative Urinary ExcretionExcretion Rate ModelingRadionuclide Content AssessmentRadionuclide KineticsRenal Excretion RateUrinary Excretion RateUrinary OutputWorkplace Impairment
Long term 239,240Pu excretion in the urine was studied in 130 'Mayak' radiochemical plant workers with different levels of health impairment. The study was based on a comparison of the 239,240Pu excretion rate measurements with the post-mortem findings of 239,240Pu body content estimates at long times after the intake. The following model is suggested for describing the urinary 239,240Pu content, (u, in a healthy human at t days after a blood intake of qos units of 239,240Pu: (u = qos x 10-4 [41exp(-0.56t) + 12exp(-0.126t) + + 1.3exp(-0.0165t) + 0.3exp(-0.00231t) + 0.13exp(-0.00002t)] The equation provides a conservative estimate based on urinalysis in dosimetric monitoring of nuclide uptake.