Clinical imaging of head and neck cancer with technetium-99m-labeled monoclonal antibody E48 IgG or F(ab')2. - Concepedia

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Clinical imaging of head and neck cancer with technetium-99m-labeled monoclonal antibody E48 IgG or F(ab')2.

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References

1994

Year

Remco de Bree, Jan C. Roos, Jasper J. Quak, W. den Hollander, Michiel W. M. van den Brekel, Jacqueline E. van der Wal, Hilde Tobi, G. B. Snow, Guus A.M.S. van Dongen

Abstract

The present study shows that RIS with either E48 F(ab')2 or E48 IgG is as valuable as the other imaging techniques. The selective accumulation of radioactivity in tumor tissues, in combination with the known intrinsic radiosensitivity of HNSCC, justifies the development of radioimmunoconjugates for radioimmunotherapy.