PubMed · 2005 · 20 citations · 0 references
Veterinary MedicineInfectious DiseasesObstetricsDiagnostic MicrobiologyMedical MicrobiologyReproductive MedicineBacterial InfectionsFever ManagementPerinatal InfectionRickettsial DiseasesTick BiologyTick-borne DiseasesInfections In PregnancyMicrobiological CurePeripheral Blood Smear MorphologyProphylactic Antibiotic TherapySupportive ManagementTick-borne PathogensTick-borne TransmissionVertical Transmission Control
BACKGROUND: Tick-borne relapsing fever (TBRF) is uncommon. Vertical transmission in the gravid woman may result in spontaneous abortion, preterm delivery or perinatal mortality. We report a case in a pregnant woman who experienced a Jarisch-Herxheimer reaction (J-HR). CASE: A 24-year-old woman at 23 weeks' gestation had a relapsing fever of unknown origin and nonspecific complaints. Her peripheral blood smear demonstrated spirochetes consistent with TBRF caused by Borrelia. Treatment with antibiotics precipitated J-HR. Supportive measures and appropriate antibiotic therapy resulted in a clinical cure and normal term delivery. CONCLUSION: The diagnosis of TBRF should be considered in individuals with recurrent fevers, especially those who have been in mountainous regions where Borrelia hermsii exists. Individuals receiving antimicrobials should be closely monitored for a J-HR.