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Detection of Moraxella bovis Antibodies in the SIgA, IgG, and IgM Classes of Immunoglobulin in Bovine Lacrimal Secretions by an Indirect Fluorescent Antibody Test
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1978
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Veterinary VaccinePathogen DetectionImmunologyIgg Immunoglobulin ClassLivestock HealthVeterinary MicrobiologyMoraxella Bovis AntibodiesBeef CalvesSerologic TestingInfection ControlParasitologyClinical IbkHealth SciencesBovine Lacrimal SecretionsIgm ClassesAntibody ScreeningVeterinary EpidemiologyClinical MicrobiologyAnimal SciencePathogenesisVeterinary ScienceImmunoglobulin EMicrobiologyMedicine
The relationship between clinical infectious bovine keratoconjunctivitis (IBK) and Moraxella bovis antibodies was evaluated in a herd of calves during one summer. The detection and the distribution of antibody response in lacrimal secretions of beef calves to natural exposure of M bovis were determined by an indirect fluorescent antibody test. Three classes of immunoglobulins--secretory IgA, IgM, and IgG--were monitored in lacrimal secretions over a 5-month period when IBK was enzootic in the herd. The 3 classes of antibody to M bovis were detected in all but 2 calves at the start of the monitoring, and the highest and most persistent M bovis antibody titers were in the IgG immunoglobulin class, and less so in IgM and secretory IgA classes. The specific antibodies present in the lacrimal secretions did not prevent the development of clinical IBK in the calves.