Formulation of interleukin-2 and interferon-alpha containing ultradeformable carriers for potential transdermal application.

Abstract

We were able to show, that IL-2 as well as IFN is trapped by transfersomes in biological active form and in sufficient concentrations for immunotherapy. In upcoming experiments these IL-2 and IFN-containing TF are used for a transdermal approach in the murine RENCA cell line model.