Veterinary MedicineToxicologyVeterinary PathologyDiagnostic ToxicologyEquine MedicineToxicologic PathologyPlant PoisoningWildlife NecropsyAnimal Plant PoisoningClinical Diagnosis Of Plant PoisoningClinicopathologic FeaturesEquine ToxicologyPasture Plant ToxicityPathologic Diagnosis Of PoisoningSerum Creatine Kinase AssessmentVeterinary Plant Poisoning
Of 10 horses in a heavily overgrazed pasture, 4 died within 1 week. Clinical signs included muscle tremors, ataxia, reluctance to walk, heavy sweating, and myoglobinuria. Serum creatine kinase, aspartate transaminase, and alkaline phosphatase activities were high. Histopathologic findings were nonspecific. On the basis of clinical signs, clinicopathologic findings, nonspecific histopathologic findings, the condition of the pasture, the identification of numerous white snakeroot plants from which trematone was extracted, and evidence that these plants had been heavily browsed, it was believed that the horses died from ingestion of Eupatorium rugosum.