Uterine Leiomyomas: Cytogenetic and Histologic Profile

Abstract

Our findings indicate that approximately 50% of leiomyomas show clonal abnormalities, which can be subdivided into four different major categories; four of five (80%) of the atypical leiomyomas showed clonal chromosome abnormalities, which in one case were complex. The results indicate that different specific chromosome abnormalities may characterize the same tumor type.