The effects of growth hormone and insulin-like growth factor on the proliferation rate and morphology of RAW 264.7 macrophages.

Abstract

(1) RAW 264.7 responded to both IGF-1 and GH equally (viability and proliferation), and (2) morphological changes were observed in all cells treated with both hormones compared to control group. This study indicates that GH hormone could induce its effect directly or indirectly through IGF-1.