Effect of antiinflammatory drugs on COX-1 and COX-2 activity in human articular chondrocytes. - Concepedia

Concepedia

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Effect of antiinflammatory drugs on COX-1 and COX-2 activity in human articular chondrocytes.

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Citations

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References

1999

Year

Francisco J. Blanco, Ramón Guitián, Juan José Moreno, Francisco Javier de Toro Santos, F. Galdo

Abstract

We found that COX-1 and COX-2 isoforms are expressed in human chondrocytes at rest and in IL-1 stimulated cells, respectively. Antiinflammatory drugs have different capacities to inhibit COX enzyme in human articular chondrocytes.