Conservative Treatment of Cystine Calculi: Effect of Oral Alpha-mercaptopropionylglycine on Cystine Stone Dissolution and on Prevention of Stone Recurrence

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No AccessJournal of Urology1 Sep 1982Conservative Treatment of Cystine Calculi: Effect of Oral Alpha-mercaptopropionylglycine on Cystine Stone Dissolution and on Prevention of Stone Recurrence Takuo Koide, Katsuhiro Kinoshita, Masato Takemoto, Sunao Yachiku, and Takao Sonoda Takuo KoideTakuo Koide More articles by this author , Katsuhiro KinoshitaKatsuhiro Kinoshita More articles by this author , Masato TakemotoMasato Takemoto More articles by this author , Sunao YachikuSunao Yachiku More articles by this author , and Takao SonodaTakao Sonoda More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)53023-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Since 1970, 35 patients with cystine calculi have been treated with oral administration of alpha-mercaptopropionylglycine (MPG) for stone dissolution and/or prevention of recurrence. Of these patients 27 received MPG for more than 1 year. The results were satisfactory. Cystine tones were dissolved completely or markedly in 7 of 21 patients and formation of new cystine stones was prevented in 23 of 27. MPG therapy was associated with fewer side effects than are reported generally with D-penicillamine. © 1982 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byKoide T, Yoshioka T, Yamaguchi S, Utsunomiya M and Sonoda T (2018) A Strategy of Cystine Stone ManagementJournal of Urology, VOL. 147, NO. 1, (112-114), Online publication date: 1-Jan-1992.Kachel T, Vijan S and Dretler S (2018) Endourological Experience With Cystine Calculi and a Treatment AlgorithmJournal of Urology, VOL. 145, NO. 1, (25-28), Online publication date: 1-Jan-1991.Singer A and Das S (2018) Cystinuria: A Review of the Pathophysiology and ManagementJournal of Urology, VOL. 142, NO. 3, (669-673), Online publication date: 1-Sep-1989.Dean Knoll L, Segura J, Patterson D, Leroy A and Smith L (2018) Long-Term Followup in Patients with Cystine Urinary Calculi Treated by Percutaneous Ultrasonic LithotripsyJournal of Urology, VOL. 140, NO. 2, (246-248), Online publication date: 1-Aug-1988.Saltzman N and Gittes R (2018) Chemolysis of Cystine CalculiJournal of Urology, VOL. 136, NO. 4, (846-849), Online publication date: 1-Oct-1986. Volume 128Issue 3September 1982Page: 513-515 Advertisement Copyright & Permissions© 1982 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Takuo Koide More articles by this author Katsuhiro Kinoshita More articles by this author Masato Takemoto More articles by this author Sunao Yachiku More articles by this author Takao Sonoda More articles by this author Expand All Advertisement PDF downloadLoading ...