Cholestasis associated with extrabiliary Hodgkin's disease. Report of three cases and review of four others.

Abstract

This report describes 3 patients with Hodgkin’s disease who developed idiopathic cholestasis. Four patients have previously been described in the literature. Although idiopathic cholestasis is usually associated with advanced lymphomas, 2 of our patients had cholestatic jaundice during early (stages I and IIA) Hodgkin’s disease, and their jaundice improved during localized radiotherapy. Hodgkin’s disease should be added to the differential diagnosis of patients with unexplained cholestatic jaundice.