The Medical Journal of Australia · 1990 · 16 citations · 28 references
MedicineNeurologyManual TherapyMovement DisordersNeuromuscular DisordersBotulinum Toxin TherapyBotulinum Toxin TreatmentMuscle DisordersTorticollis ManagementBotulinum NeurotoxinBotulinum ToxinsPilot Study Design
Nineteen patients with spasmodic torticollis, unresponsive to standard therapy, were administered local injections of botulinum-A toxin into the affected muscles. During an average follow-up period of 11.5 months, a more than 25% improvement was noted in 14 of 19 patients. All those with purely focal dystonia and 9 of 10 patients with a disease history of less than three years benefited from treatment. Side effects were insignificant and transient. Botulinum toxin is a very effective and safe method of treatment for spasmodic torticollis.
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DOUBLE-BLIND STUDY OF BOTULINUM TOXIN IN SPASMODIC TORTICOLLIS
JosephK.C Tsui, A. Jon Stoessl, Andrew Eisen et al. · The Lancet · 1986 · 810 citations
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Stanley Fahn · PubMed · 1988 · 523 citations
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Medicine, Neurology, Psychiatry +8