Change in Bilirubin Level Following Acute Myocardial Infarction Is an Index for Heme Oxygenase Activation

Abstract

These results suggest that heme oxygenase (HO) was activated following AMI, and it was detectable in the serum. Our data provide the first evidence of HO-1 induction following stress in humans. The change in bilirubin level may be a novel index for high collateral flow formation following AMI.