How Well Do In Vitro Particle Size Measurements Predict Drug Delivery In Vivo?

Comparison of bronchodilator responses and deposition patterns of salbutamol inhaled from a pressurised metered dose inhaler, as a dry powder, and as a nebulised solution.

B. M. Z. Zainudin, Martyn F. Biddiscombe, S E Tolfree et al. · Thorax · 1990 · 176 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Pressurised aerosol deposition in the human lung with and without an "open" spacer device.

Stephen P. Newman, Andrew R. Clark, N Talaee et al. · Thorax · 1989 · 154 citations · Full text

Pharmacy, Nuclear Medicine, Pharmacology +16

The use of laser diffraction for the evaluation of the aerosol clouds generated by medical nebulizers

Andrew Clark · International Journal of Pharmaceutics · 1995 · 145 citations

Natural Sciences, Biophysics, Biomedical Optics +14

Comparison of Gamma Scintigraphy and a Pharmacokinetic Technique for Assessing Pulmonary Deposition of Terbutaline Sulphate Delivered by Pressurized Metered Dose Inhaler

Stephen P. Newman, K.P. Steed, G. Hooper et al. · Pharmaceutical Research · 1995 · 115 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Tissue Attenuation Corrections in Gamma Scintigraphy

Gary R. Pitcairn, Stephen P. Newman · Journal of Aerosol Medicine · 1997 · 98 citations

Medicine, Nuclear Medicine, Radiology +13