Chronic cigarette smoking induces an oxidantantioxidant imbalance in the testis.

Abstract

Chronic cigarette smoke inhalation is associated with an increase in the level of oxidants and a simultaneous decrease in the level of antioxidants in the rat testis. This abnormality of the oxidant-antioxidant balance may be one of the mechanisms leading to testicular tissue damage and abnormal spermatogenesis in the rat testis following chronic inhalation of cigarette smoke.