Microvascular protective role of pericytes in melatonin-treated spinal cord injury in the C57BL/6 mice. - Concepedia

Concepedia

Publication | Closed Access

Microvascular protective role of pericytes in melatonin-treated spinal cord injury in the C57BL/6 mice.

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References

2014

Year

Yingli Jing, Qingbin Wu, Xiaochen Yuan, Bingwei Li, Mingming Liu, Xiaoyan Zhang, Shuying Liu, Hongwei Li, Ruijuan Xiu

Abstract

Melatonin ameliorated the loss of blood vessels and disruption of BSCB to exert a protective effect on SCI, which might be mediated by increased pericyte coverage. The upregulation of Ang1 in pericytes could inhibit inflammation and apoptosis to protect the microvessels.