PubMed · 1980 · 31 citations · 0 references
Life SciencesBiochemistryLipid BiochemistryCholesterol MetabolismLipid DisordersLipid MetabolismLipid Metabolism DisordersLipoprotein MetabolismMetabolic DiseaseAtherogenic Lipoprotein AssessmentAtherosclerosis RiskAtherosclerotic Risk AssessmentLipid Risk AssessmentPlasma Cholesterol Levels
Patients with hyperlipoproteinemia, who were treated with diet and lipid-lowering drugs, were followed up over a period of six to twelve months. The various coefficients of serum concentrations of total cholesterol, triglycerides, phospholipids, HDL-cholesterol, LDL-cholesterol, and the ratio HDL-cholesterol/total cholesterol and LDL/HDL (socalled atherosclerosis-index) were estimated. Among all factors the "atherosclerosis-index" was the most reliable indicator of an increased risk with a margin of 7,9 +/- 1,3%. The widest variation was seen, as expected, among the concentrations of triglycerides (20,1 +/- 3,0%).