PubMed · 1985 · 82 citations · 0 references
PharmacyPharmacotherapyPsychiatryMental Health CarePsychiatric PharmacotherapyPsychopharmacologyAntidepressant PharmacotherapyAntidepressant TherapyAntipsychotic TherapyDepression ManagementDepression PharmacotherapyTreatment Of Mental DisordersCombination Antipsychotic TherapyDelusional Disorder DiagnosisElectroconvulsive Therapy For DepressionProspective EffectivenessTricyclic Antidepressant Therapy
The treatment responses of 597 patients with delusional depression from 17 studies were compared. Patients were treated with either tricyclic anti-depressants (TCAs), antipsychotics (APs), the combination of TCA/AP, or electroconvulsive therapy (ECT). The overall responses were 34% in the group treated with TCA, 51% in the AP group, 77% in the TCA/AP group, and 82% in the ECT group. Prospective studies to define the risk/benefit ratios of the more effective therapies, TCA/AP and ECT, are needed.