Buspirone therapy for maladaptive behavior and anxiety in developmentally disabled persons.

John J. Ratey, Robert Sovner, Edwin J. Mikkelsen, Hilary E. Chmielinski

PubMed · 1989 · 83 citations · 0 references

Concepts

Abstract

The authors used buspirone, a new anxiolytic agent that has a low side effect profile, to treat 14 developmentally disabled individuals who demonstrated anxiety as well as aggressive and self-injurious behaviors. Nine of the 14 individuals responded favorably to the drug. The authors present case reports for 3 of the responders and discuss the clinical implications of buspirone therapy.